Zyprexa (Olanzapine) is used to treat schizophrenia and bipolar disorder (manic depression).



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Drug Uses

Zyprexa is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression).

How to use

Use Zyprexa as directed by your doctor.

Take Zyprexa by mouth with or without food.
Drinking extra fluids while you are taking Zyprexa is recommended. Check with your doctor for instructions.
Continue to take Zyprexa even if you feel well. Do not miss any doses.
Ask your health care provider any questions you may have about how to use Zyprexa.
Drug Class and Mechanism

Zyprexa is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Missed Dose

If you miss a dose of Zyprexa , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


Store Zyprexa at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Zyprexa out of the reach of children and away from pets.


Do not use Zyprexa if:

you are allergic to any ingredient in Zyprexa.
Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Zyprexa . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of seizures, heart problems (eg, heart failure; fast, slow, or irregular heartbeat), abnormal electrocardiogram (ECG), heart attack, stroke, blood vessel problems, high blood cholesterol levels, or high or low blood pressure
if you have a history of liver problems, stomach or bowel problems (eg, decreased muscle movement), enlarged prostate, narrow-angle glaucoma, neuroleptic malignant syndrome (NMS), aspiration pneumonia, or suicidal thoughts or attempts
if you have Alzheimer disease, dementia, or trouble swallowing
if you have diabetes or are very overweight, or if a family member has had diabetes
if you have had high blood prolactin levels or a history of certain types of cancer (eg, breast, pancreas, pituitary), or if you are at risk for breast cancer
if you are dehydrated, drink alcohol, or smoke, or you will be exposed to high temperatures

Some MEDICINES MAY INTERACT with Zyprexa . Tell your health care provider if you are taking any other medicines, especially any of the following:
Alpha blockers (eg, doxazosin), diazepam, or medicine for high blood pressure because the risk of low blood pressure and fainting may be increased
Anticholinergics (eg, scopolamine), fluvoxamine, or lorazepam because they may increase the risk of Zyprexa 's side effects
Carbamazepine, HIV protease inhibitors (eg, ritonavir), omeprazole, or rifampin because they may decrease Zyprexa 's effectiveness
Dopamine receptor agonists (eg, pramipexole) or levodopa because their effectiveness may be decreased by Zyprexa